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GeneQ18026214· pop 8· linked from 304 articles

GNA12

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Also known as NNX3, RMP, gep, G protein subunit alpha 12, HG1M1

Guanine nucleotide-binding protein subunit alpha-12 is a protein that in humans is encoded by the GNA12 gene.

Gene data

GNA12
Name
G protein subunit alpha 12
Type
protein-coding
Position
2,721,820–2,870,786 (−)
Aliases
HG1M1, NNX3, RMP, gep
Ensembl
ENSG00000146535
RefSeq RNA
NM_001282440.1, NM_001282441.2, NM_001293092.2, NM_007353.3
RefSeq protein
NP_001269369.1, NP_001269370.1, NP_001280021.1, NP_031379.2

Predicted to enable D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in regulation of TOR signaling and regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Pathways

MAPK signaling pathway - Homo sapiens (human)cGMP-PKG signaling pathway - Homo sapiens (human)Sphingolipid signaling pathway - Homo sapiens (human)Phospholipase D signaling pathway - Homo sapiens (human)Vascular smooth muscle contraction - Homo sapiens (human)Long-term depression - Homo sapiens (human)Regulation of actin cytoskeleton - Homo sapiens (human)Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)Pathogenic Escherichia coli infection - Homo sapiens (human)Human cytomegalovirus infection - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

G protein subunit alpha 12

Symbol
GNA12
Biotype
Protein coding
Organism
Homo sapiens
Location
7:2,721,820-2,870,786
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

4 sections
Contents
  • Interactions and functions
  • See also
  • References
  • External links

Guanine nucleotide-binding protein subunit alpha-12 is a protein that in humans is encoded by the GNA12 gene.

== Interactions and functions ==

Excerpted from Wikipedia’s “GNA12” article, available under the CC BY-SA 4.0 licence.

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