GPR78

Also known as G protein-coupled receptor 78

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.

Gene data

GPR78

Name: G protein-coupled receptor 78
Type: protein-coding
Position: 8,558,725–8,619,761 (+)
Ensembl: ENSG00000155269
RefSeq RNA: NM_080819.5, NR_045511.3
RefSeq protein: NP_543009.2

The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011].

Gene Ontology

Biological process

G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway

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Article

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Contents

References
Further reading

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]