GRK2

Name

G protein-coupled receptor kinase 2

Type

protein-coding

Position

67,266,391–67,286,557 (+)

Aliases

ADRBK1, BARK1, BETA-ARK1

Ensembl

ENSG00000173020

RefSeq RNA

NM_001619.5, XM_011544773.2, XM_054367819.1, XR_007062455.1, XR_008488347.1

RefSeq protein

NP_001610.2, XP_011543075.1, XP_054223794.1

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017].

via MyGene.info

Gene · Ensembl

G protein-coupled receptor kinase 2

Symbol

GRK2

Biotype

Protein coding

Organism

Homo sapiens

Location

11:67,266,351-67,286,562

Strand

Forward (+)

Assembly

GRCh38

Described at

UniProt

uniprot.org →

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Wikidata facts

Image

Protein ADRBK1 PDB 1bak.png

via Wikidata · CC0