Also known as IMD35, JTK1, tyrosine kinase 2, Non-receptor tyrosine-protein kinase
protein-coding gene in the species Homo sapiens
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. [provided by RefSeq, Sep 2020].
Biological process
Molecular function
via MyGene.info
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).