Also known as GIG8, ID2A, ID2H, bHLHb26, inhibitor of DNA binding 2, HLH protein, inhibitor of DNA binding 2
DNA-binding protein inhibitor ID-2 is a protein that in humans is encoded by the ID2 gene.
Gene data
ID2- Name
- inhibitor of DNA binding 2
- Type
- protein-coding
- Position
- 8,678,845–8,684,461 (+)
- Aliases
- GIG8, ID2A, ID2H, bHLHb26
- Ensembl
- ENSG00000115738
- RefSeq RNA
- NM_002166.5
- RefSeq protein
- NP_002157.2
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
inhibitor of DNA binding 2
- Symbol
- ID2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:8,678,845-8,684,461
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1632
- exact match
- identifiers.org/ncbigene/3398
- genomic end
- 8684461
- genomic start
- 8818975
- cytogenetic location
- 2p25.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
DNA-binding protein inhibitor ID-2 is a protein that in humans is encoded by the ID2 gene.
== Function ==