LAIR1
Sign in to saveAlso known as CD305, LAIR-1, leukocyte associated immunoglobulin like receptor 1
Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene. LAIR1 has also been designated as CD305 (cluster of differentiation 305).
In the Vinony graph
Vinony's link graph records 364 inbound references to LAIR1, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
Vinony files it under Clusters of differentiation, Genes on human chromosome 19 and Immunoglobulin superfamily.
Vinony links it to 5 Wikipedia language editions.
Gene data
LAIR1- Name
- leukocyte associated immunoglobulin like receptor 1
- Type
- protein-coding
- Aliases
- CD305, LAIR-1
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
via MyGene.info
Gene · Ensembl
leukocyte associated immunoglobulin like receptor 1
- Symbol
- LAIR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR19_4_CTG3_1:334,105-353,279
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 48097
- exact match
- identifiers.org/ncbigene/3903
- found in taxon
- Homo sapiens
- chromosome
- human chromosome 19
- genomic start
- 54865362
- genomic end
- 54882165
- cytogenetic location
- 19q13.42
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene. LAIR1 has also been designated as CD305 (cluster of differentiation 305).
== Function ==
Excerpted from Wikipedia’s “LAIR1” article, available under the CC BY-SA 4.0 licence.