NEK2
Sign in to saveAlso known as HsPK21, NEK2A, NLK1, PPP1R111, RP67, NIMA related kinase 2
Serine/threonine-protein kinase Nek2 is an enzyme that in humans is encoded by the NEK2 gene.
Gene data
NEK2- Name
- NIMA related kinase 2
- Type
- protein-coding
- Position
- 211,658,251–211,675,663 (−)
- Aliases
- HsPK21, NEK2A, NLK1, PPP1R111, RP67
- Ensembl
- ENSG00000117650
- RefSeq RNA
- NM_001204182.2, NM_001204183.2, NM_002497.4
- RefSeq protein
- NP_001191111.1, NP_001191112.1, NP_002488.1
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
NIMA related kinase 2
- Symbol
- NEK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:211,658,251-211,675,663
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein NEK2 PDB 2jav.png
Show 8 more facts
- HomoloGene ID
- 74441
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4751
- genomic end
- 211848960
- genomic start
- 211836114
- chromosome
- human chromosome 1
- cytogenetic location
- 1q32.3
- expressed in
- trabecular bone
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Serine/threonine-protein kinase Nek2 is an enzyme that in humans is encoded by the NEK2 gene.
== Interactions ==
Excerpted from Wikipedia’s “NEK2” article, available under the CC BY-SA 4.0 licence.