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prednimustine
Sign in to savePrednimustine, sold under the brand names Mostarina and Sterecyst, is a medication which is used in chemotherapy in the treatment of leukemias and lymphomas. It is the ester formed from two other drugs, prednisolone and chlorambucil. Rarely, it has been associated with myoclonus.
In the Vinony graph
Vinony's link graph records 590 inbound references to prednimustine, and connects out to mometasone furoate, fludrocortisone and ulipristal acetate.
It is catalogued under topics including Anilines, Antineoplastic drugs and Carboxylate esters.
Vinony links it to 7 Wikipedia language editions.
Chemical data
- Formula
- C35H45Cl2NO6
- Molecular weight
- 646.6 g/mol
- IUPAC name
- [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- lymphoma, neoplasm
via ChEMBL · EBI
Research
189 papers- Prednimustine.IARC monographs on the evaluation of carcinogenic risks to humans · 1990
- Prednimustine.Seminars in oncology · 1986
- Prednimustine in advanced breast cancer: a review.Seminars in oncology · 1986
- [Myoclonus induced by prednimustine].Neurologia (Barcelona, Spain) · 1998
- Prednimustine treatment in malignant lymphomas.Oncology · 1989
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 645.262
- Has use
- medication
Show 5 more facts
- chemical formula
- C₃₅H₄₅Cl₂NO₆
- canonical SMILES
- CC12CC(C3C(C1CCC2(C(=O)COC(=O)CCCC4=CC=C(C=C4)N(CCCl)CCCl)O)CCC5=CC(=O)C=CC35C)O
- isomeric SMILES
- C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COC(=O)CCCC4=CC=C(C=C4)N(CCCl)CCCl)O)CCC5=CC(=O)C=C[C@]35C)O
- subject has role
- alkylating antineoplastic agent
- Commons category
- Prednimustine
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 434002897 | IUPAC_name = [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate | image = Prednimustine.svg | image_class = skin-invert-image | width = 250px
| tradename = Mostarina, Sterecyst | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “prednimustine” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0