پردنیموستین

Prednimustine, sold under the brand names Mostarina and Sterecyst, is a medication which is used in chemotherapy in the treatment of leukemias and lymphomas. It is the ester formed from two other drugs, prednisolone and chlorambucil. Rarely, it has been associated with myoclonus.

In the Vinony graph

Within Vinony's link graph, پردنیموستین is referenced by 590 other articles, and connects out to mometasone furoate, fludrocortisone and ulipristal acetate.

It sits within the topics Anilines, Antineoplastic drugs and Carboxylate esters.

Its subject is documented across 7 Wikipedia language editions.

Chemical data

Formula: C35H45Cl2NO6
Molecular weight: 646.6 g/mol
IUPAC name: [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: lymphoma, neoplasm

via ChEMBL · EBI

Research

189 papers

Prednimustine.IARC monographs on the evaluation of carcinogenic risks to humans · 1990
Prednimustine.Seminars in oncology · 1986
Prednimustine in advanced breast cancer: a review.Seminars in oncology · 1986
[Myoclonus induced by prednimustine].Neurologia (Barcelona, Spain) · 1998
Prednimustine treatment in malignant lymphomas.Oncology · 1989

via PubMed

Wikidata facts

Subclass of: chemical compound
Has part: carbon
Mass: 645.262
Has use: medication

Show 5 more facts

chemical formula: C₃₅H₄₅Cl₂NO₆
canonical SMILES: CC12CC(C3C(C1CCC2(C(=O)COC(=O)CCCC4=CC=C(C=C4)N(CCCl)CCCl)O)CCC5=CC(=O)C=CC35C)O
isomeric SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COC(=O)CCCC4=CC=C(C=C4)N(CCCl)CCCl)O)CCC5=CC(=O)C=C[C@]35C)O
subject has role: alkylating antineoplastic agent
Commons category: Prednimustine

Sources (2)

via Wikidata · CC0