SALL3
Sign in to saveAlso known as ZNF796, spalt-like transcription factor 3, spalt like transcription factor 3
Sal-like protein 3, also known as zinc finger protein SALL3, is a protein that in humans in encoded by the SALL3 gene.
Gene data
SALL3- Name
- spalt like transcription factor 3
- Type
- protein-coding
- Aliases
- ZNF796
This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis. [provided by RefSeq, Oct 2011].
via MyGene.info
Gene · Ensembl
spalt like transcription factor 3
- Symbol
- SALL3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:78,979,419-79,002,677
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18142
- exact match
- identifiers.org/ncbigene/27164
- genomic start
- 78979818
- genomic end
- 76762677
- cytogenetic location
- 18q23
Sources (3)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Sal-like protein 3, also known as zinc finger protein SALL3, is a protein that in humans in encoded by the SALL3 gene.
==References==