Structure via PubChem · Public domain (PubChem)
talastine
Sign in to saveTalastine (trade name Ahanon) is an antihistamine.
In the Vinony graph
Within Vinony's link graph, talastine is referenced by 341 other articles, and connects out to (RS)-meclizine, medication and proton.
It sits within the topics Benzyl compounds, Chemical pages without DrugBank identifier and Drugs with no legal status.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C19H21N3O
- Molecular weight
- 307.4 g/mol
- IUPAC name
- 4-benzyl-2-[2-(dimethylamino)ethyl]phthalazin-1-one
- SMILES
- CN(C)CCN1C(=O)C2=CC=CC=C2C(=N1)CC3=CC=CC=C3
- InChIKey
- LCAAMXMULMCKLJ-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 35.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- allergic disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 307.168
Show 2 more facts
- canonical SMILES
- CN(C)CCN1C(=O)C2=CC=CC=C2C(=N1)CC3=CC=CC=C3
- chemical formula
- C₁₉H₂₁N₃O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- References
- External links
Talastine (trade name Ahanon) is an antihistamine.
==Synthesis== The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with dimethylaminoethyl chloride.
Excerpted from Wikipedia’s “talastine” article, available under the CC BY-SA 4.0 licence.
Connections
(RS)-meclizine
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medication
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proton
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respiratory system
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chemical formula
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molar mass
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PubMed
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histamine
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chloride
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amides
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L-histidine
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antidepressant
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CAS Registry Number
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PubChem
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Medical Subject Headings
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Anatomical Therapeutic Chemical Classification System
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amitriptyline
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cetirizine
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simplified molecular input line entry specification
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histamine antagonist
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