TFRC
Sign in to saveAlso known as CD71, T9, TFR, TFR1, TR, TRFR, p90, IMD46
protein-coding gene in the species Homo sapiens
Gene data
TFRC- Name
- transferrin receptor
- Type
- protein-coding
- Position
- 196,012,511–196,082,162 (−)
- Aliases
- CD71, IMD46, T9, TFR, TFR1, TR, TRFR, p90
- Ensembl
- ENSG00000072274
- RefSeq RNA
- NM_001128148.3, NM_001313965.2, NM_001313966.2, NM_003234.4, XM_047448786.1
- RefSeq protein
- NP_001121620.1, NP_001300894.1, NP_001300895.1, NP_003225.2, XP_047304742.1
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015].
Gene Ontology
Biological process
Molecular function
Pathways
HIF-1 signaling pathway - Homo sapiens (human)Endocytosis - Homo sapiens (human)Phagosome - Homo sapiens (human)Ferroptosis - Homo sapiens (human)Hematopoietic cell lineage - Homo sapiens (human)Developmental BiologySignal TransductionSignaling by Rho GTPasesMembrane Traffickingtrans-Golgi Network Vesicle Budding
via MyGene.info
Gene · Ensembl
transferrin receptor
- Symbol
- TFRC
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:196,012,511-196,082,162
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TFRC PDB 1cx8.png
Show 5 more facts
- HomoloGene ID
- 2429
- exact match
- identifiers.org/ncbigene/7037
- genomic end
- 196082096
- genomic start
- 195754054
- cytogenetic location
- 3q29
Sources (3)
via Wikidata · CC0
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