azapropazone

Also known as apazone

Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Goldshield under the tradename Rheumox.

In the Vinony graph

Vinony's link graph records 279 inbound references to azapropazone, and connects out to salicylic acid, metamizole sodium and prescription drug.

It sits within the topics Benzotriazines, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.

Vinony links it to 11 Wikipedia language editions.

Chemical data

Formula: C16H20N4O2
Molecular weight: 300.36 g/mol
IUPAC name: 5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
SMILES: CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C
InChIKey: MPHPHYZQRGLTBO-UHFFFAOYSA-N
XLogP: 4
Polar surface area: 56.2 Å²
H-bond donors: 0
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: rheumatic disease

via ChEMBL · EBI

Research

252 papers

Azapropazone - its place in the management of rheumatoid conditions.Current medical research and opinion · 1976
The pharmacology and pharmacokinetics of azapropazone - a review.Current medical research and opinion · 1976
The amphiprotic character of azapropazone and its relevance to the gastric mucosa.Archives of toxicology · 1990
Azapropazone in aspirin intolerance.Allergy · 1999
Apazone.2006

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 300.15862587999993
Has use: medication

Show 4 more facts

Commons category: Azapropazone
chemical formula: C₁₆H₁₈N₄O₂
defined daily dose: 0.75
canonical SMILES: CCCC1C(=O)N2c3cc(ccc3N=C(N2C1=O)N(C)C)C

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

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Contents

References

Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Goldshield under the tradename Rheumox.

It was available in the UK as a prescription-only drug, with restrictions due to certain contra-indications and side-effects. Azopropazone has now been discontinued in the British National Formulary.

Excerpted from Wikipedia’s “azapropazone” article, available under the CC BY-SA 4.0 licence.