BIRC3
Sign in to saveAlso known as AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, BIRC3 is referenced by 42 other articles, and connects out to PubMed, Ensembl genome database project and protein.
It sits within the topics Genes on human chromosome 11 and Oncogenes.
Its subject is documented across 7 Wikipedia language editions.
Gene data
BIRC3- Name
- baculoviral IAP repeat containing 3
- Type
- protein-coding
- Position
- 102,317,451–102,339,403 (+)
- Aliases
- AIP1, API2, CIAP2, HAIP1, HIAP1, IAP-1, MALT2, MIHC, RNF49, c-IAP2
- Ensembl
- ENSG00000023445
- RefSeq RNA
- NM_001165.5, NM_182962.3, XM_054368613.1
- RefSeq protein
- NP_001156.1, NP_892007.1, XP_054224588.1
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
baculoviral IAP repeat containing 3
- Symbol
- BIRC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:102,317,451-102,339,403
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BIRC3 PDB 2uvl.png
Show 8 more facts
- HomoloGene ID
- 899
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/330
- genomic end
- 102210134
- genomic start
- 102188215
- chromosome
- human chromosome 11
- cytogenetic location
- 11q22.2
- expressed in
- tonsil
Sources (3)
via Wikidata · CC0