Also known as ETK, PSCTK2, PSCTK3, BMX non-receptor tyrosine kinase
protein-coding gene in the species Homo sapiens
Gene data
BMX- Name
- BMX non-receptor tyrosine kinase
- Type
- protein-coding
- Chromosome
- X
- Aliases
- ETK, PSCTK2, PSCTK3
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016].
via MyGene.info
Gene · Ensembl
BMX non-receptor tyrosine kinase
- Symbol
- BMX
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:15,464,246-15,556,529
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein BMX PDB 2EKX.png
Show 5 more facts
- HomoloGene ID
- 20411
- exact match
- identifiers.org/ncbigene/660
- genomic end
- 15574652
- genomic start
- 15482369
- cytogenetic location
- Xp22.2
Sources (3)
via Wikidata · CC0