CDSN
Sign in to saveAlso known as D6S586E, HTSS, HTSS1, HYPT2, PSS, PSS1, corneodesmosin, S
Corneodesmosin is a protein that in humans is encoded by the CDSN gene.
In the Vinony graph
Within Vinony's link graph, CDSN is referenced by 281 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under topics including Genes on human chromosome 6 and Plakins.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CDSN- Name
- corneodesmosin
- Type
- protein-coding
- Chromosome
- HSCHR6_MHC_MANN_CTG1
- Position
- 2,425,650–2,430,956 (−)
- Aliases
- HTSS, HTSS1, HYPT2, PSS, PSS1
- Ensembl
- ENSG00000237165
- RefSeq RNA
- NM_001264.5
- RefSeq protein
- NP_001255.4
This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6. [provided by RefSeq, Dec 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
corneodesmosin
- Symbol
- CDSN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:31,115,087-31,120,446
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 48005
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1041
- chromosome
- human chromosome 6
- genomic start
- 31115087
- genomic end
- 31088223
- cytogenetic location
- 6p21.33
- expressed in
- duodenum
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Corneodesmosin is a protein that in humans is encoded by the CDSN gene.
This gene encodes a protein found in corneodesmosomes, which localize to the human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.
Excerpted from Wikipedia’s “CDSN” article, available under the CC BY-SA 4.0 licence.