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GeneQ18042907· pop 7· linked from 361 articles

Also known as CD164L1, TEM1, CD248 molecule

Endosialin is a protein that in humans is encoded by the CD248 gene.

Gene data

CD248
Name
CD248 molecule
Type
protein-coding
Aliases
CD164L1, TEM1

Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration. Predicted to act upstream of or within several processes, including anatomical structure regression; lymph node development; and positive regulation of endothelial cell apoptotic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

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Gene · Ensembl

CD248 molecule

Symbol
CD248
Biotype
Protein coding
Organism
Homo sapiens
Location
11:66,314,494-66,317,044
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
10699
genomic end
66084515
genomic start
66314494
cytogenetic location
11q13.2
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Endosialin is a protein that in humans is encoded by the CD248 gene.

Endosialin is a member of the “Group XIV”, a novel family of C-type lectin transmembrane receptors which play a role not only in cell–cell adhesion processes but also in host defence. This family comprise three other members, CLEC14A, CD93 and Thrombomodulin the latter of which are better characterized.

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