CGB2

Also known as chorionic gonadotropin beta subunit 2, chorionic gonadotropin subunit beta 2

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 4 inbound references to CGB2, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 19.

Vinony links it to 4 Wikipedia language editions.

Gene data

CGB2

Name: chorionic gonadotropin subunit beta 2
Type: protein-coding
Position: 49,031,890–49,033,238 (+)
Ensembl: ENSG00000104818
RefSeq RNA: NM_001319065.2, NM_033378.2
RefSeq protein: NP_001305994.1, NP_203696.2

The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB2 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017). However, a 163 aa protein, translated from a different frame, is about the same size, and shares 98% identity with other CGB subunits. [provided by RefSeq, Jul 2008].