Also known as lutropin, ICSH, lutrophin, glyco-Lutropin, interstitial cell–stimulating hormone, luteinizing hormone, LH
instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-378969)
Glyco-Lutropin is a protein complex found in human cells that plays a role in reproductive processes by interacting with hormonal signals in the body. The extracellular region refers to the part of this complex that sits outside of cells, where it can interact with other molecules to transmit important biological messages.
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Luteinizing hormone (LH, also known as luteinising hormone, lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. In females, an acute rise of LH known as an LH surge, triggers ovulation and development of the corpus luteum. In males, where LH had also been called interstitial cell stimulating hormone (ICSH), it stimulates Leydig cell production of testosterone. It acts synergistically with follicle-stimulating hormone (FSH).
Etymology
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).