DOCK6
Sign in to saveAlso known as AOS2, ZIR1, dedicator of cytokinesis 6
protein-coding gene in the species Homo sapiens
Gene data
DOCK6- Name
- dedicator of cytokinesis 6
- Type
- protein-coding
- Aliases
- AOS2, ZIR1
This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011].
via MyGene.info
Gene · Ensembl
dedicator of cytokinesis 6
- Symbol
- DOCK6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:11,199,295-11,262,533
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 83291
- exact match
- identifiers.org/ncbigene/57572
- genomic end
- 11262524
- genomic start
- 11309971
- cytogenetic location
- 19p13.2
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 19
Entity
Ensembl genome database project
Entity
sequence homology
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protein
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International Standard Book Number
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
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bibcode
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phospholipids
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human genome
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Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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neuroblastoma
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cell signaling
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