DOCK6
Sign in to saveAlso known as AOS2, ZIR1, dedicator of cytokinesis 6
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, DOCK6 is referenced by 33 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 5 Wikipedia language editions.
Gene data
DOCK6- Name
- dedicator of cytokinesis 6
- Type
- protein-coding
- Position
- 11,199,295–11,262,533 (−)
- Aliases
- AOS2, ZIR1
- Ensembl
- ENSG00000130158
- RefSeq RNA
- NM_001367830.1, NM_020812.4, XM_005260000.3, XM_006722804.4, XM_011528150.2
- RefSeq protein
- NP_001354759.1, NP_065863.2, XP_005260057.1, XP_006722867.1, XP_011526452.1
This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
dedicator of cytokinesis 6
- Symbol
- DOCK6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:11,199,295-11,262,533
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 83291
- genetic association
- Adams-Oliver syndrome
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57572
- genomic end
- 11262524
- genomic start
- 11309971
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.2
- expressed in
- gastric mucosa
via Wikidata · CC0