DNAH5

Also known as CILD3, DNAHC5, HL1, KTGNR, PCD, dynein axonemal heavy chain 5

Dynein axonemal heavy chain 5 is a protein that in humans is encoded by the DNAH5 gene.

Gene data

DNAH5

Name: dynein axonemal heavy chain 5
Type: protein-coding
Aliases: CILD3, DNAHC5, HL1, KTGNR, PCD

This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009].

via MyGene.info

Gene · Ensembl

dynein axonemal heavy chain 5

Symbol: DNAH5
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:13,690,328-14,011,818
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

exact match: identifiers.org/ncbigene/1767
HomoloGene ID: 1048
genomic end: 14011818
genomic start: 13690328
cytogenetic location: 5p15.2

Sources (4)

via Wikidata · CC0

~1 min read

Article

3 sections

Contents

References
External links
Further reading

Dynein axonemal heavy chain 5 is a protein that in humans is encoded by the DNAH5 gene.

DNAH5 is a protein-coding gene.1 It provides the instructions for synthesizing a protein that belongs to a microtubule-associated protein complex made of heavy, light and intermediate chains.2 DNAH5 is responsible for making the heavy chain 5, found within the outer dynein arms of cilia.1 It will function as a force generating protein by using ATP, producing the power stroke for cilia.3