linsitinib

Also known as OSI-9606

Linsitinib is an experimental drug candidate for the treatment of various types of cancer. It is an inhibitor of the insulin receptor and of the insulin-like growth factor 1 receptor (IGF-1R). This prevents tumor cell proliferation and induces tumor cell apoptosis.

Chemical data

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule
Indications: neoplasm, small cell lung carcinoma, hepatocellular carcinoma, prostate adenocarcinoma

via ChEMBL · EBI

Wikidata facts

Mass: 421.19026035599995

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isomeric SMILES: C[C@]1(C[C@@H](C1)C=2N3C(C(=NC=C3)N)=C(N2)C4=CC5=NC(=CC=C5C=C4)C6=CC=CC=C6)O
canonical SMILES: CC1(CC(C1)C=2N3C(C(=NC=C3)N)=C(N2)C4=CC5=NC(=CC=C5C=C4)C6=CC=CC=C6)O
chemical formula: C₂₆H₂₃N₅O
Commons category: Linsitinib

Sources (3)

via Wikidata · CC0

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