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GeneQ18044822· pop 6· linked from 69 articles

Also known as 4SPAN2, CD20L4, CFFM4, MS4A8, membrane spanning 4-domains A7

Membrane-spanning 4-domains subfamily A member 7 is a protein that in humans is encoded by the MS4A7 gene.

Gene data

MS4A7
Name
membrane spanning 4-domains A7
Type
protein-coding
Aliases
4SPAN2, CD20L4, CFFM4, MS4A8

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

membrane spanning 4-domains A7

Symbol
MS4A7
Biotype
Protein coding
Organism
Homo sapiens
Location
11:60,363,737-60,395,954
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
10922
genomic end
60163424
genomic start
60378485
cytogenetic location
11q12.2
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Membrane-spanning 4-domains subfamily A member 7 is a protein that in humans is encoded by the MS4A7 gene.

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

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