pipamperone
Also known as dipiperone, floropipamide, R-3345, R 3345, 1'-(3-(p-fluorobenzoyl)propyl)-(1,4'-bipiperidine)-4'-carboxamide, p-fluoro-gamma-(4-piperidino-4-carbamoylpiperidino)butyrophenone, Carpiperone
Pipamperone (INN, USAN, BAN), sold under the brand name Dipiperon, is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia and as a sleep aid for depression. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
Research
162 papers- Pipamperone Population Pharmacokinetics Related to Effectiveness and Side Effects in Children and Adolescents.Clinical pharmacokinetics · 2020
- Pipamperone and delirium: a preliminary evaluation of its effectiveness in the management of delirium and its subtypes.Swiss medical weekly · 2017
- Pipamperone concentrations and organ distribution in postmortem cases with and without overdoses.International journal of legal medicine · 2026
- [Overdosing of pipamperone from a squeeze bottle].Nederlands tijdschrift voor geneeskunde · 2018
- Pipamperone (Dipiperon, R3345) in troublesome mental retardates: a double-blind placebo controlled cross-over study with long-term follow-up.Acta psychiatrica Scandinavica · 1975
via PubMed
~3 min read
Article
5 sectionsContents
- Medical uses
- Pharmacology
- Antidepressant effects
- See also
- References
Pipamperone (INN, USAN, BAN), sold under the brand name Dipiperon, is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia and as a sleep aid for depression. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
==Medical uses== Pipamperone was developed for use as an antipsychotic in the treatment of schizophrenia.