SASS6
Sign in to saveAlso known as SAS-6, SAS6, MCPH14, SAS-6 centriolar assembly protein
Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.
In the Vinony graph
Vinony's link graph records 33 inbound references to SASS6, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 5 Wikipedia language editions.
Gene data
SASS6- Name
- SAS-6 centriolar assembly protein
- Type
- protein-coding
- Position
- 100,083,563–100,132,955 (−)
- Aliases
- MCPH14, SAS-6, SAS6
- Ensembl
- ENSG00000156876
- RefSeq RNA
- NM_001304829.2, NM_194292.3, XM_017000486.2, XM_047447884.1, XM_047447889.1
- RefSeq protein
- NP_001291758.1, NP_919268.1, XP_016855975.1, XP_047303840.1, XP_047303845.1
The protein encoded by this gene is a central component of centrioles and is necessary for their duplication and function. Centrioles adopt a cartwheel-shaped structure, with the encoded protein forming the hub and spokes inside a microtubule cylinder. Defects in this gene are a cause of autosomal recessive primary microcephaly. [provided by RefSeq, Oct 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
SAS-6 centriolar assembly protein
- Symbol
- SASS6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:100,083,563-100,132,955
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 45668
- exact match
- identifiers.org/ncbigene/163786
- found in taxon
- Homo sapiens
- genomic end
- 100598511
- genomic start
- 100549119
- chromosome
- human chromosome 1
- cytogenetic location
- 1p21.2
- expressed in
- appendix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.
== Function ==
Excerpted from Wikipedia’s “SASS6” article, available under the CC BY-SA 4.0 licence.