SOCS6

Also known as CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4

Suppressor of cytokine signaling 6 is a protein that in humans is encoded by the SOCS6 gene.

Gene data

SOCS6

Name: suppressor of cytokine signaling 6
Type: protein-coding
Aliases: CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4

The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

suppressor of cytokine signaling 6

Symbol: SOCS6
Biotype: Protein coding
Organism: Homo sapiens
Location: 18:70,288,876-70,330,199
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 3120
exact match: identifiers.org/ncbigene/9306
genomic end: 70330199
genomic start: 70289045
cytogenetic location: 18q22.2

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Suppressor of cytokine signaling 6 is a protein that in humans is encoded by the SOCS6 gene.

The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI) protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.