UGT2B10
Sign in to saveAlso known as UDPGT2B10, UDP glucuronosyltransferase family 2 member B10
UDP-glucuronosyltransferase 2B10 is an enzyme that in humans is encoded by the UGT2B10 gene. It is responsible for glucuronidation of nicotine and cotinine. Due to common hypomorphic alleles of UGT2B10, glucuronidation contributes relatively little to nicotine metabolism in most people.
In the Vinony graph
Within Vinony's link graph, UGT2B10 is referenced by 409 other articles, and connects out to glucuronosyltransferase, PubMed and human chromosome 4.
It is catalogued under the topic Genes on human chromosome 4.
Its subject is documented across 4 Wikipedia language editions.
Gene data
UGT2B10- Name
- UDP glucuronosyltransferase family 2 member B10
- Type
- protein-coding
- Position
- 68,815,895–68,835,737 (+)
- Aliases
- UDPGT2B10
- Ensembl
- ENSG00000275190
- RefSeq RNA
- NM_001075.6, NM_001144767.3, NM_001290091.2, XM_017008585.3, XM_054328543.1
- RefSeq protein
- NP_001066.1, NP_001138239.1, NP_001277020.1, XP_016864074.1, XP_054184518.1
Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
UDP glucuronosyltransferase family 2 member B10
- Symbol
- UGT2B10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR4_1_CTG9:392,012-407,215
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein UGT2B10 PDB 2o6l.png
Show 7 more facts
- cytogenetic location
- 4q13.2
- HomoloGene ID
- 117389
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7365
- chromosome
- human chromosome 4
- genomic start
- 68815994
- genomic end
- 68832023
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
UDP-glucuronosyltransferase 2B10 is an enzyme that in humans is encoded by the UGT2B10 gene. It is responsible for glucuronidation of nicotine and cotinine. Due to common hypomorphic alleles of UGT2B10, glucuronidation contributes relatively little to nicotine metabolism in most people.
== See also == UGT2B17
Excerpted from Wikipedia’s “UGT2B10” article, available under the CC BY-SA 4.0 licence.