BACH1
Sign in to saveAlso known as BACH-1, BTBD24, BTB domain and CNC homolog 1
Gen der Spezies Homo sapiens
Gene data
BACH1- Name
- BTB domain and CNC homolog 1
- Type
- protein-coding
- Position
- 29,194,071–29,630,751 (+)
- Aliases
- BACH-1, BTBD24
- Ensembl
- ENSG00000156273
- RefSeq RNA
- NM_001011545.1, NM_001186.4, NM_206866.3, NR_027655.3
- RefSeq protein
- NP_001177.1, NP_996749.1
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
BACH transcriptional regulator 1
- Symbol
- BACH1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:29,194,071-29,630,751
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BACH1 PDB 2ihc.png
Show 9 more facts
- HomoloGene ID
- 916
- genetic association
- pancreatic cancer
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/571
- chromosome
- human chromosome 21
- genomic start
- 30566392
- genomic end
- 31003071
- cytogenetic location
- 21q21.3
- expressed in
- amniotic fluid
via Wikidata · CC0