CD247

Name

CD247 molecule

Type

protein-coding

Position

167,425,027–167,518,640 (−)

Aliases

CD3-ZETA, CD3H, CD3Q, CD3Z, CD3ZETA, IMD25, T3Z, TCRZ

Ensembl

ENSG00000198821

RefSeq RNA

NM_000734.4, NM_001378515.1, NM_001378516.1, NM_198053.3, XM_011510144.3

RefSeq protein

NP_000725.1, NP_001365444.1, NP_001365445.1, NP_932170.1, XP_011508446.1

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

CD247 molecule

Symbol

CD247

Biotype

Protein coding

Organism

Homo sapiens

Location

1:167,425,027-167,518,640

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein CD247 PDB 2hac.png

via Wikidata · CC0