CRHR2
Sign in to saveAlso known as CRF-RB, CRF2, CRFR2, HM-CRF, corticotropin releasing hormone receptor 2
protein-coding gene in the species Homo sapiens
Gene data
CRHR2- Name
- corticotropin releasing hormone receptor 2
- Type
- protein-coding
- Position
- 30,651,444–30,700,129 (−)
- Aliases
- CRF-RB, CRF2, CRFR2, HM-CRF
- Ensembl
- ENSG00000106113
- RefSeq RNA
- NM_001202475.1, NM_001202481.1, NM_001202482.2, NM_001202483.2, NM_001883.5
- RefSeq protein
- NP_001189404.1, NP_001189410.1, NP_001189411.1, NP_001189412.1, NP_001874.2
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
corticotropin releasing hormone receptor 2
- Symbol
- CRHR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:30,651,444-30,700,129
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 55612
- exact match
- identifiers.org/ncbigene/1395
- genomic end
- 30739745
- genomic start
- 30651942
- cytogenetic location
- 7p14.3
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