CRHR1

Name

corticotropin releasing hormone receptor 1

Type

protein-coding

Position

45,784,277–45,835,828 (+)

Aliases

CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRHR, CRHR1L

Ensembl

ENSG00000276191

RefSeq RNA

NM_001145146.2, NM_001145147.2, NM_001145148.2, NM_001303018.2, NM_001303020.2

RefSeq protein

NP_001138618.1, NP_001138619.1, NP_001138620.1, NP_001289947.1, NP_001289949.1

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016].

via MyGene.info

Wikidata facts

Image

6PB0 CRF1 receptor.png

via Wikidata · CC0