fluvastatin
Also known as XUO320, Canef®, Lescol®, (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid, (+)-(3R,5S)-fluvastatin
Fluvastatin is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.
Chemical data
- Formula
- C24H26FNO4
- Molecular weight
- 411.5 g/mol
- IUPAC name
- (E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
- SMILES
- CC(C)N1C2=CC=CC=C2C(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C3=CC=C(C=C3)F
- InChIKey
- FJLGEFLZQAZZCD-MCBHFWOFSA-N
- XLogP
- 3.5
- Polar surface area
- 82.7 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
2,370 papers~3 min read
Article
9 sectionsContents
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacodynamics
- Pharmacokinetics
- Names
- Research
- References
Fluvastatin is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.
It was patented in 1982 and approved for medical use in 1994. It is on the World Health Organization's List of Essential Medicines.