HOXA5
Sign in to saveAlso known as HOX1, HOX1.3, HOX1C, homeobox A5
Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.
Gene data
HOXA5- Name
- homeobox A5
- Type
- protein-coding
- Position
- 27,141,052–27,143,719 (−)
- Aliases
- HOX1, HOX1.3, HOX1C
- Ensembl
- ENSG00000106004
- RefSeq RNA
- NM_019102.4
- RefSeq protein
- NP_061975.2
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
homeobox A5
- Symbol
- HOXA5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:27,141,052-27,143,719
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~2 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- See also
- References
- External links
Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.
== Function ==
Excerpted from Wikipedia’s “HOXA5” article, available under the CC BY-SA 4.0 licence.