HOXB5
Sign in to saveAlso known as HHO.C10, HOX2, HOX2A, HU-1, Hox2.1, homeobox B5
Homeobox protein Hox-B5 is a protein that in humans is encoded by the HOXB5 gene.
Gene data
HOXB5- Name
- homeobox B5
- Type
- protein-coding
- Position
- 48,591,257–48,594,179 (−)
- Aliases
- HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
- Ensembl
- ENSG00000120075
- RefSeq RNA
- NM_002147.4
- RefSeq protein
- NP_002138.1
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
homeobox B5
- Symbol
- HOXB5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:48,591,257-48,594,179
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Homeobox protein Hox-B5 is a protein that in humans is encoded by the HOXB5 gene.
== Function ==
Excerpted from Wikipedia’s “HOXB5” article, available under the CC BY-SA 4.0 licence.