HTR6
Sign in to saveAlso known as 5-HT6, 5-HT6R, 5-HT6 receptor, 5-hydroxytryptamine receptor 6
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, HTR6 is referenced by 1,854 other articles, and connects out to N-methylserotonin, PubMed and atypical antipsychotic.
Vinony files it under Genes on human chromosome 1 and Serotonin receptors.
Its subject is documented across 8 Wikipedia language editions.
Gene data
HTR6- Name
- 5-hydroxytryptamine receptor 6
- Type
- protein-coding
- Position
- 19,664,837–19,680,966 (+)
- Aliases
- 5-HT6, 5-HT6R
- Ensembl
- ENSG00000158748
- RefSeq RNA
- NM_000871.3
- RefSeq protein
- NP_000862.1
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
5-hydroxytryptamine receptor 6
- Symbol
- HTR6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:19,664,837-19,680,966
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 673
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3362
- genomic end
- 19680966
- genomic start
- 19664875
- chromosome
- human chromosome 1
- cytogenetic location
- 1p36.13
- expressed in
- inferior ganglion of vagus nerve
via Wikidata · CC0