HTR6

Also known as 5-HT6, 5-HT6R, 5-HT6 receptor, 5-hydroxytryptamine receptor 6

protein-coding gene in the species Homo sapiens

Gene data

HTR6

Name: 5-hydroxytryptamine receptor 6
Type: protein-coding
Position: 19,664,875–19,680,966 (+)
Aliases: 5-HT6, 5-HT6R
Ensembl: ENSG00000158748
RefSeq RNA: NM_000871.3
RefSeq protein: NP_000862.1

This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013].