Also known as Cmyb, c-myb, c-myb_CDS, efg, MYB proto-oncogene, transcription factor
protein-coding gene in the species Homo sapiens
Gene data
MYB- Name
- MYB proto-oncogene, transcription factor
- Type
- protein-coding
- Aliases
- Cmyb, c-myb, c-myb_CDS, efg
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
via MyGene.info
Gene · Ensembl
MYB proto-oncogene, transcription factor
- Symbol
- MYB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:135,180,897-135,219,173
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Research
11,417 papers- MYB transcription factors in Arabidopsis.Trends in plant science · 2010
- The R2R3-MYB gene family in Arabidopsis thaliana.Current opinion in plant biology · 2001
- Multiple Functions of MYB Transcription Factors in Abiotic Stress Responses.International journal of molecular sciences · 2021
- c-MYB and DMTF1 in Cancer.Cancer investigation · 2019
- Emerging role of MYB transcription factors in cancer drug resistance.Cancer drug resistance (Alhambra, Calif.) · 2024
via PubMed
Wikidata facts
- Image
- Protein MYB PDB 1guu.png
Show 5 more facts
- HomoloGene ID
- 31311
- exact match
- identifiers.org/ncbigene/4602
- genomic end
- 135540311
- genomic start
- 135181308
- cytogenetic location
- 6q23.3
via Wikidata · CC0
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