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phenglutarimide
Sign in to saveAlso known as 3-(2-diethylaminoethyl)-4-phenylpiperidine-2,6-dione
Phenglutarimide (brand names Aturbal and Aturbane) is an anticholinergic used as an antiparkinsonian agent.
In the Vinony graph
Within Vinony's link graph, phenglutarimide is referenced by 457 other articles, and connects out to atropine, muscarinic acetylcholine receptor family and medication.
Vinony files it under Chemical pages without DrugBank identifier, Diethylamino compounds and Drugboxes which contain changes to verified fields.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C17H24N2O2
- Molecular weight
- 288.4 g/mol
- IUPAC name
- 3-[2-(diethylamino)ethyl]-3-phenylpiperidine-2,6-dione
- SMILES
- CCN(CC)CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- InChIKey
- BFMBKRQFMIILCH-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 49.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Parkinson disease
via ChEMBL · EBI
Research
14 papers- Stereoselective recognition of the enantiomers of phenglutarimide and of six related compounds by four muscarinic receptor subtypes.British journal of pharmacology · 1996
- [Phenglutarimide in the medical treatment of parkinsonism].La Semana medica · 1960
- The fate of phenglutarimide hydrochloride in the rat and man.Xenobiotica; the fate of foreign compounds in biological systems · 1973
- Stereoselectivity at muscarinic receptor subtypes: observations with the enantiomers of phenglutarimide.Chirality · 1989
- [Aturban (phenglutarimide), a new therapeutic drug for parkinsonism; comparative investigation on the therapy of parkinsonism].Schweizerische medizinische Wochenschrift · 1958
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 288.184
Show 3 more facts
- chemical formula
- C₁₇H₂₄N₂O₂
- canonical SMILES
- CCN(CC)CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- subject has role
- anticholinergic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Phenglutarimide (brand names Aturbal and Aturbane) is an anticholinergic used as an antiparkinsonian agent.
== References ==
Excerpted from Wikipedia’s “phenglutarimide” article, available under the CC BY-SA 4.0 licence.