RND3
Sign in to saveAlso known as ARHE, Rho8, RhoE, memB, Rho family GTPase 3
Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3.
In the Vinony graph
Vinony's link graph records 232 inbound references to RND3, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 2.
Vinony links it to 4 Wikipedia language editions.
Gene data
RND3- Name
- Rho family GTPase 3
- Type
- protein-coding
- Position
- 150,468,195–150,539,011 (−)
- Aliases
- ARHE, Rho8, RhoE, memB
- Ensembl
- ENSG00000115963
- RefSeq RNA
- NM_001254738.1, NM_005168.5
- RefSeq protein
- NP_001241667.1, NP_005159.1
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
Rho family GTPase 3
- Symbol
- RND3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:150,468,195-150,539,011
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RND3 PDB 1gwn.png
Show 9 more facts
- HomoloGene ID
- 21074
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/390
- genomic end
- 151395525
- genomic start
- 151324709
- chromosome
- human chromosome 2
- cytogenetic location
- 2q23.3
- expressed in
- lactiferous duct
- Commons category
- RhoE (RND3)
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Regulation
- Interactions
- References
- Further reading
Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3.
Like other members of the Rho family of Ras-related GTPases it regulates the organization of the actin cytoskeleton in response to extracellular growth factors.
Excerpted from Wikipedia’s “RND3” article, available under the CC BY-SA 4.0 licence.