甲狀腺促素釋素

Also known as TRH, IPR008857, protirelin, Thyrotropic releasing hormone, Protirelin, Thyroliberin, Thyrotropin releasing hormone, 5-oxo-L-prolyl-L-histidyl-L-prolinamide

hormone

Chemical data

Formula: C16H22N6O4
Molecular weight: 362.38 g/mol
IUPAC name: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
SMILES: C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N
InChIKey: XNSAINXGIQZQOO-SRVKXCTJSA-N
XLogP: -2.5
Polar surface area: 150 Å²
H-bond donors: 4
H-bond acceptors: 5
Formal charge: 0

via PubChem

Research

15,591 papers

Article · 中文

甲狀腺促素釋素（Thyrotropin-releasing hormone，TRH）簡稱甲釋素，是由下視丘所製造的肽類激素，能夠調節腦下垂體前葉分泌促甲状腺激素（甲促素，thyroid-stimulating hormone，TSH）與催乳素。 TRH除了腦部以外，也能夠在消化管與胰島檢測到。合成TRH被利用來檢查下視丘與甲狀腺功能是否正常。

Abstract from DBpedia / Wikipedia · CC BY-SA