TSPAN4
Sign in to saveAlso known as NAG-2, NAG2, TETRASPAN, TM4SF7, TSPAN-4, tetraspanin 4
Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene.
In the Vinony graph
Vinony's link graph records 72 inbound references to TSPAN4, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Vinony links it to 7 Wikipedia language editions.
Gene data
TSPAN4- Name
- tetraspanin 4
- Type
- protein-coding
- Aliases
- NAG-2, NAG2, TETRASPAN, TM4SF7, TSPAN-4
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
tetraspanin 4
- Symbol
- TSPAN4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:840,686-867,120
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2453
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7106
- genomic end
- 867116
- genomic start
- 842812
- chromosome
- human chromosome 11
- cytogenetic location
- 11p15.5
- expressed in
- tibial nerve
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
Excerpted from Wikipedia’s “TSPAN4” article, available under the CC BY-SA 4.0 licence.