TSPAN4
Sign in to saveAlso known as NAG-2, NAG2, TETRASPAN, TM4SF7, TSPAN-4, tetraspanin 4
Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene.
Gene data
TSPAN4- Name
- tetraspanin 4
- Type
- protein-coding
- Aliases
- NAG-2, NAG2, TETRASPAN, TM4SF7, TSPAN-4
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
tetraspanin 4
- Symbol
- TSPAN4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:840,686-867,120
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2453
- exact match
- identifiers.org/ncbigene/7106
- genomic end
- 867116
- genomic start
- 842812
- cytogenetic location
- 11p15.5
Sources (4)
via Wikidata · CC0
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Article
3 sectionsContents
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- Further reading
Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.