ADGRA2
Sign in to saveAlso known as G protein-coupled receptor 124, TEM5, GPR124, adhesion G protein-coupled receptor A2
Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
In the Vinony graph
Vinony's link graph records 489 inbound references to ADGRA2, and connects out to PubMed, Ensembl genome database project and cell surface receptor.
Vinony files it under Genes on human chromosome 8 and G protein-coupled receptors.
Vinony links it to 5 Wikipedia language editions.
Gene data
ADGRA2- Name
- adhesion G protein-coupled receptor A2
- Type
- protein-coding
- Position
- 37,784,191–37,844,896 (+)
- Aliases
- GPR124, TEM5
- Ensembl
- ENSG00000020181
- RefSeq RNA
- NM_032777.10, XM_011544481.3, XM_011544482.3, XM_011544483.3, XM_054360257.1
- RefSeq protein
- NP_116166.9, XP_011542783.1, XP_011542784.1, XP_011542785.1, XP_054216232.1
Predicted to enable G protein-coupled receptor activity. Involved in positive regulation of canonical Wnt signaling pathway. Part of Wnt signalosome. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor A2
- Symbol
- ADGRA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:37,784,191-37,844,896
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 13112
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25960
- genomic end
- 37702414
- genomic start
- 37641709
- chromosome
- human chromosome 8
- cytogenetic location
- 8p11.23
- expressed in
- superficial temporal artery
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
== Interactions ==
Excerpted from Wikipedia’s “ADGRA2” article, available under the CC BY-SA 4.0 licence.