Also known as TM7LN3, EMR1, adhesion G protein-coupled receptor E1
EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene.
This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
via MyGene.info
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EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene.
EMR1 is a member of the adhesion GPCR family characterized by an extended extracellular region containing EGF-like domains. EMR1 is predominantly expressed on the surface of macrophages and plays a significant role in immune response modulation and inflammation. Its expression has been linked to various inflammatory diseases.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).