GFRA4
Sign in to saveAlso known as GDNF family receptor alpha 4
GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.
In the Vinony graph
Within Vinony's link graph, GFRA4 is referenced by 352 other articles, and connects out to human chromosome 20, Ensembl genome database project and protein.
It is catalogued under the topic Genes on human chromosome 20.
Its subject is documented across 5 Wikipedia language editions.
Gene data
GFRA4- Name
- GDNF family receptor alpha 4
- Type
- protein-coding
- Position
- 3,659,248–3,663,483 (−)
- Ensembl
- ENSG00000125861
- RefSeq RNA
- NM_022139.4, NM_145762.3, NM_145763.1, XM_005260793.2, XM_054323832.1
- RefSeq protein
- NP_071422.1, NP_665705.1, XP_005260850.1, XP_054179807.1
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
GDNF family receptor alpha 4
- Symbol
- GFRA4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:3,659,248-3,663,483
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- exact match
- identifiers.org/ncbigene/64096
- HomoloGene ID
- 10565
- found in taxon
- Homo sapiens
- genomic end
- 3644046
- genomic start
- 3659248
- chromosome
- human chromosome 20
- cytogenetic location
- 20p13
- expressed in
- kidney
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.
==See also== GFRα
Excerpted from Wikipedia’s “GFRA4” article, available under the CC BY-SA 4.0 licence.