F2RL3
Sign in to saveAlso known as PAR4, F2R like thrombin/trypsin receptor 3, F2R like thrombin or trypsin receptor 3
Protease-activated receptor 4 (PAR-4), also known as coagulation factor II (thrombin) receptor-like 3, is a protein that in humans is encoded by the F2RL3 gene.
Gene data
F2RL3- Name
- F2R like thrombin or trypsin receptor 3
- Type
- protein-coding
- Aliases
- PAR4
This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016].
via MyGene.info
Gene · Ensembl
F2R like thrombin or trypsin receptor 3
- Symbol
- F2RL3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:16,888,844-16,892,606
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 36148
- exact match
- identifiers.org/ncbigene/9002
- genomic end
- 17003417
- genomic start
- 16888999
- cytogenetic location
- 19p13.11
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- See also
- References
- Further reading
Protease-activated receptor 4 (PAR-4), also known as coagulation factor II (thrombin) receptor-like 3, is a protein that in humans is encoded by the F2RL3 gene.
== Function ==