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GeneQ17918564· pop 5· linked from 486 articles

Also known as PAR-3, PAR3, coagulation factor II thrombin receptor like 2

Protease activated receptor 3 (PAR-3) also known as coagulation factor II receptor-like 2 (F2RL2) and thrombin receptor-like 2, is a protein that in humans is encoded by the F2RL2 gene.

Gene data

F2RL2
Name
coagulation factor II thrombin receptor like 2
Type
protein-coding
Aliases
PAR-3, PAR3

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012].

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Gene · Ensembl

coagulation factor II thrombin receptor like 2

Symbol
F2RL2
Biotype
Protein coding
Organism
Homo sapiens
Location
5:76,615,423-76,623,425
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
36151
genomic end
76623413
genomic start
75911307
cytogenetic location
5q13.3
Sources (3)

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4 sections
Contents
  • Function
  • See also
  • References
  • Further reading

Protease activated receptor 3 (PAR-3) also known as coagulation factor II receptor-like 2 (F2RL2) and thrombin receptor-like 2, is a protein that in humans is encoded by the F2RL2 gene.

== Function ==

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