RELB
Sign in to saveAlso known as I-REL, IREL, REL-B, RELB proto-oncogene, NF-kB subunit, IMD53
gene umano
Gene data
RELB- Name
- RELB proto-oncogene, NF-kB subunit
- Type
- protein-coding
- Position
- 45,001,431–45,038,194 (+)
- Aliases
- I-REL, IMD53, IREL, REL-B
- Ensembl
- ENSG00000104856
- RefSeq RNA
- NM_001411087.1, NM_006509.4, XM_005259128.3, XM_047439189.1, XM_047439190.1
- RefSeq protein
- NP_001398016.1, NP_006500.2, XP_005259185.1, XP_047295145.1, XP_047295146.1
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
RNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA bindingDNA-binding transcription factor activity
Cellular component
Pathways
MAPK signaling pathway - Homo sapiens (human)NF-kappa B signaling pathway - Homo sapiens (human)Osteoclast differentiation - Homo sapiens (human)C-type lectin receptor signaling pathway - Homo sapiens (human)Human T-cell leukemia virus 1 infection - Homo sapiens (human)Epstein-Barr virus infection - Homo sapiens (human)Cytokine Signaling in Immune systemAdaptive Immune SystemInnate Immune SystemImmune System
via MyGene.info
Gene · Ensembl
RELB proto-oncogene, NF-kB subunit
- Symbol
- RELB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:45,001,431-45,038,194
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RELB PDB 1zk9.png
Show 7 more facts
- HomoloGene ID
- 4747
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5971
- genomic end
- 45541452
- genomic start
- 45001449
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.32
via Wikidata · CC0