TPP2
Sign in to saveAlso known as TPP-2, TPPII, Tripeptidyl peptidase II, tripeptidyl peptidase 2, TPP-II, IMD78
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, TPP2 is referenced by 152 other articles, and connects out to PubMed, human chromosome 13 and Ensembl genome database project.
Vinony files it under EC 3.4.14, Genes on human chromosome 13 and Proteases.
Its subject is documented across 5 Wikipedia language editions.
Gene data
TPP2- Name
- tripeptidyl peptidase 2
- Type
- protein-coding
- Position
- 102,596,936–102,679,958 (+)
- Aliases
- IMD78, TPP-2, TPP-II, TPPII
- Ensembl
- ENSG00000134900
- RefSeq RNA
- NM_001330588.2, NM_001367947.1, NM_001446028.1, NM_003291.4, NR_160411.1
- RefSeq protein
- NP_001317517.1, NP_001354876.1, NP_001432957.1, NP_003282.2, XP_005254127.1
This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tripeptidyl peptidase 2
- Symbol
- TPP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:102,596,936-102,679,958
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 2471
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7174
- genomic end
- 103331521
- genomic start
- 102596986
- chromosome
- human chromosome 13
- cytogenetic location
- 13q33.1
Sources (4)
via Wikidata · CC0