TPP2
Sign in to saveAlso known as TPP-2, TPPII, Tripeptidyl peptidase II, tripeptidyl peptidase 2, TPP-II, IMD78
protein-coding gene in the species Homo sapiens
Gene data
TPP2- Name
- tripeptidyl peptidase 2
- Type
- protein-coding
- Position
- 102,596,958–102,679,958 (+)
- Aliases
- IMD78, TPP-2, TPP-II, TPPII
- Ensembl
- ENSG00000134900
- RefSeq RNA
- NM_001330588.2, NM_001367947.1, NM_001446028.1, NM_003291.4, NR_160411.1
- RefSeq protein
- NP_001317517.1, NP_001354876.1, NP_001432957.1, NP_003282.2, XP_005254127.1
This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tripeptidyl peptidase 2
- Symbol
- TPP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:102,596,936-102,679,958
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2471
- exact match
- identifiers.org/ncbigene/7174
- genomic end
- 103331521
- genomic start
- 102596986
- cytogenetic location
- 13q33.1
Sources (4)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 13
Entity
Ensembl genome database project
Entity
enzyme
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
bibcode
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
cofactor
Entity
myosin
Entity
Enzyme Commission number
Entity
peptidase
Entity
ligases
Entity