TRAF5
Sign in to saveAlso known as MGC:39780, RNF84, TNF receptor associated factor 5
TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.
Gene data
TRAF5- Name
- TNF receptor associated factor 5
- Type
- protein-coding
- Position
- 211,326,325–211,375,036 (+)
- Aliases
- MGC:39780, RNF84
- Ensembl
- ENSG00000082512
- RefSeq RNA
- NM_001033910.3, NM_001319207.2, NM_004619.4, NM_145759.3, XM_011509957.4
- RefSeq protein
- NP_001029082.1, NP_001306136.1, NP_004610.1, NP_665702.1, XP_011508259.2
The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
TNF receptor associated factor 5
- Symbol
- TRAF5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:211,326,325-211,375,117
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 27079
- exact match
- identifiers.org/ncbigene/7188
- genomic end
- 211548288
- genomic start
- 211499957
- cytogenetic location
- 1q32.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.
== Function ==