BMPR2

Name

bone morphogenetic protein receptor type 2

Type

protein-coding

Position

202,375,835–202,567,751 (+)

Aliases

BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK

Ensembl

ENSG00000204217

RefSeq RNA

NM_001204.7, NM_001445553.1, NM_001445554.1, NM_001445555.1, NM_001445556.1

RefSeq protein

NP_001195.2, NP_001432482.1, NP_001432483.1, NP_001432484.1, NP_001432485.1

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020].

via MyGene.info

Gene · Ensembl

bone morphogenetic protein receptor type 2

Symbol

BMPR2

Biotype

Protein coding

Organism

Homo sapiens

Location

2:202,375,835-202,567,751

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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