CD101 molecule
Sign in to saveAlso known as cell surface glycoprotein V7, immunoglobulin superfamily member 2, EWI-101, glu-Trp-Ile EWI motif-containing protein 101, CD101, leukocyte surface protein
Immunoglobulin superfamily, member 2 (IGSF2) also known as CD101 (Cluster of Differentiation 101), is a human gene.
In the Vinony graph
Within Vinony's link graph, CD101 molecule is referenced by 361 other articles, and connects out to PubMed, Ensembl genome database project and CD1.
It sits within the topics Clusters of differentiation and Genes on human chromosome 1.
Its subject is documented across 5 Wikipedia language editions.
Protein · UniProt
Immunoglobulin superfamily member 2
- Gene
- CD101
- Organism
- Homo sapiens (Human)
- Length
- 1,021 aa
- Molecular mass
- 115,109 Da
- Evidence
- 1: Evidence at protein level
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells
Swiss-Prot (reviewed) · via UniProt
Wikidata facts
- Instance of
- protein
Show 3 more facts
- P352
- John Walker
- cell component
- extracellular exosome
- found in taxon
- Homo sapiens
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Immunoglobulin superfamily, member 2 (IGSF2) also known as CD101 (Cluster of Differentiation 101), is a human gene.
==See also== Cluster of differentiation
Excerpted from Wikipedia’s “CD101 molecule” article, available under the CC BY-SA 4.0 licence.